Image domain pansharpening method and system for spectral CT with large pixel energy discriminating detectors

A hybrid CT dataset is obtained from a combination of a integrating detector and a photon-counting detector. The hybrid CT dataset contains low-resolution photon-counting data and high-resolution integrating data. High-resolution panchromatic images are generated from the high-resolution integrating data, and low-resolution spectral images are generated from the low-resolution photon-counting data. The high-resolution panchromatic images inherit the resolution properties of the integrating detector while the low-resolution spectral images inherit the spectral information of the photon-counting detector. Subsequently, the low resolution spectral images are pansharpened based upon at least one high resolution panchromatic image that lacks spectral information according to a pansharpening algorithm.