Published December 12, 2000 | Version v1
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Method for construction of bacterial strains with increased succinic acid production

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Description

A fermentation process for producing succinic acid is provided comprising selecting a bacterial strain that does not produce succinic acid in high yield, disrupting the normal regulation of sugar metabolism of said bacterial strain, and combining the mutant bacterial strain and selected sugar in anaerobic conditions to facilitate production of succinic acid. Also provided is a method for changing low yield succinic acid producing bacteria to high yield succinic acid producing bacteria comprising selecting a bacterial strain having a phosphotransferase system and altering the phosphotransferase system so as to allow the bacterial strain to simultaneously metabolize different sugars.

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Additional details

Identifiers

Patent application number
US 6793198 A
Patent number
US 6159738 A
Other
oai:uchicago.tind.io:8673

Dates

Patent filed
1998-04-28

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Microbiology