Centers and Institutes
Published May 17, 2021 | Version v1
Journal article Open

Roadmap on biology in time varying environments

Creators

  • 1. University of Chicago
  • 2. Northwestern University
  • 3. University of Edinburgh
  • 4. Princeton University
  • 5. Massachusetts Institute of Technology
  • 6. PSL Research University
  • 7. University of California, Los Angeles
  • 8. University of Michigan
  • 9. New York University
  • 10. University of Illinois at Urbana-Champaign

Description

Biological organisms experience constantly changing environments, from sudden changes in physiology brought about by feeding, to the regular rising and setting of the Sun, to ecological changes over evolutionary timescales. Living organisms have evolved to thrive in this changing world but the general principles by which organisms shape and are shaped by time varying environments remain elusive. Our understanding is particularly poor in the intermediate regime with no separation of timescales, where the environment changes on the same timescale as the physiological or evolutionary response. Experiments to systematically characterize the response to dynamic environments are challenging since such environments are inherently high dimensional. This roadmap deals with the unique role played by time varying environments in biological phenomena across scales, from physiology to evolution, seeking to emphasize the commonalities and the challenges faced in this emerging area of research.

Data availability

No new data were created or analysed in this study.

Files

Murugan_2021_Phys._Biol._18_041502.pdf

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Additional details

Identifiers

DOI
10.1088/1478-3975/abde8d
Other
oai:uchicago.tind.io:14092

Funding

National Institute of Diabetes and Digestive and Kidney Diseases
R01DK090625
National Institute of Diabetes and Digestive and Kidney Diseases
R01DK113011
National Institute of Diabetes and Digestive and Kidney Diseases
R01DK100814
National Institute of Diabetes and Digestive and Kidney Diseases
R01DK050203
National Institute on Aging
P01AG011412
Chicago Biomedical Consortium
University of Chicago
P60DK020595

UChicago Information

Division(s)
Physical Sciences Division, Pritzker School of Molecular Engineering
Department(s)
Molecular Genetics and Cell Biology, Physics
Center(s) or Institute(s)
Center for the Physics of Evolving Systems, James Franck Institute