Published November 11, 2024 | Version v1
Journal article Open

Overview of Therapeutic Ultrasound Applications and Safety Considerations: 2024 Update

  • 1. University of Chicago
  • 2. Focused Ultrasound Foundation
  • 3. University of Cincinnati
  • 4. Alpheus Medical, Inc.
  • 5. University of Rochester
  • 6. University of Michigan
  • 7. U.S. Food and Drug Administration

Description

A 2012 review of therapeutic ultrasound was published to educate researchers and physicians on potential applications and concerns for unintended bioeffects (doi: 10.7863/jum.2012.31.4.623). This review serves as an update to the parent article, highlighting advances in therapeutic ultrasound over the past 12 years. In addition to general mechanisms for bioeffects produced by therapeutic ultrasound, current applications, and the pre-clinical and clinical stages are outlined. An overview is provided for image guidance methods to monitor and assess treatment progress. Finally, other topics relevant for the translation of therapeutic ultrasound are discussed, including computational modeling, tissue-mimicking phantoms, and quality assurance protocols.

Data availability

Data sharing is not applicable to this article as no new data were created or analyzed in this study.

Files

Overview-of-Therapeutic-Ultrasound-Applications-and-Safety-Considerations.pdf

Additional details

Identifiers

DOI
10.1002/jum.16611
Other
oai:uchicago.tind.io:13964

Funding

National Institutes of Health
R01 HL133334
National Institutes of Health
R01 EB0352309
National Institutes of Health
R01 HL148451
National Science Foundation
2426784
American Cancer Society
RSG-21-171-01-ET
Children's Neuroblastoma Cancer Foundation
Focused Ultrasound Foundation

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Radiology