Biological Sciences Division
Published April 21, 2011 | Version v1
Patent Open

USE OF THE COMBINATION COMPRISING TEMOZOLOMIDE AND TNF-ALPHA FOR TREATING GLIOBLASTOMA

Creators

  • 1. University of Chicago
  • 2. Dana-Farber Cancer Institute

Contributors

Description

Disclosed are methods of synergistically inhibiting growth of a glioma cell comprising contacting the cell with temozolomide and TNFα, or with temozolomide, TNFα, and radiation. Also disclosed are methods of synergistically inhibiting growth of a glioma in a human cancer patient comprising administering temozolomide and TNFα, or with temozolomide, TNFα, and radiation. Pharmaceutical combinations and therapeutic combinations suitable for use in the methods of the invention are also disclosed.

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Additional details

Identifiers

Patent application number
US 97195310 A
Patent number
US 2011/0091375 A1
Other
oai:uchicago.tind.io:9539

Dates

Patent filed
2010-12-17

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Radiation and Cellular Oncology, Medicine