Published February 5, 2008 | Version v1
Patent Open

Identification of novel factors that block programmed cell death or apoptosis by targeting JNK

Description

Methods and compositions for modulating apoptosis by acting on the c-Jun-N-terminal kinase (JNK) pathway and assays for the isolation of agents capable of modulating apoptosis, including modulators of the JNK pathway are disclosed. A method of modulating JNK pathway independent of Gadd46beta is disclosed. Methods and compositions are presented for the preparation and use of novel therapeutic compositions for modulating diseases and conditions associated with elevated or decreased apoptosis.

Files

US7326418.pdf

Files (4.3 MB)

Name Size Download all
md5:bd5746ff95e48d00fc43ab2852f1f771
4.3 MB Preview Download

Additional details

Identifiers

Patent application number
US 36504 A
Patent number
US 7326418 B2
Other
oai:uchicago.tind.io:8791

Dates

Patent filed
2004-11-29

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Radiation and Cellular Oncology, Ben May Department for Cancer Research