Published February 7, 2024 | Version v1
Journal article Open

ATTR Gene Variants in HCM

Description

Hypertrophic cardiomyopathy is the most common inherited cardiomyopathy, with a prevalence of 1:200 to 1:500. Cardiac amyloidosis, another cardiomyopathy caused by myocardial deposition of abnormally folded TTR protein, can be acquired or hereditary. The presence of pathogenic TTR gene variants in patients with phenotypic HCM is an underrecognized and clinically important entity.

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Additional details

Identifiers

DOI
10.1016/j.jaccas.2024.102236
Other
oai:uchicago.tind.io:11132

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Medicine