Published March 21, 2019 | Version v1
Patent Open

SMALL MOLECULES INHIBITORS OF RAD51

Description

Embodiments concern methods and small molecule compositions for selectively inhibiting RAD51-mediated D-loop formation while preserving RAD51's ability to form nucleoprotein filaments. The selective RAD51 D-loop formation activity inhibitors DNA repair while minimizing replication-associated toxicity in normal tissue.

Files

US20190083491.pdf

Files (2.1 MB)

Name Size Download all
md5:6670f6570c1a77823cd302c0c35b8346
2.1 MB Preview Download

Additional details

Identifiers

Patent application number
US 201716081662 A
Patent number
US 2019/0083491 A1
Other
oai:uchicago.tind.io:8072

Dates

Patent filed
2017-03-02

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Radiation and Cellular Oncology