Published October 5, 2010 | Version v1
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Increased T-cell tumor infiltration by mutant LIGHT

  • 1. University of Chicago

Contributors

Patent applicant:

Description

Mutant LIGHT expressed in a tumor environment elicited high levels of chemokines and adhesion molecules, accompanied by massive infiltration of naïve T lymphocytes. Methods and compositions to elicit immune responses against tumors including tumor volume reduction and reduced metastasis using mutant LIGHT are disclosed.

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Additional details

Identifiers

Patent application number
US 86562304 A
Patent number
US 7807784 B2
Other
oai:uchicago.tind.io:8795

Dates

Patent filed
2004-06-10

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Pathology