Published April 22, 2014 | Version v1
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Compositions and methods for treating atherosclerosis

Description

Peptides and mimetics of selected domains of mammalian serum amyloid A isoform 2.1 (SAA2.1) and compounds and compositions thereof are provided that enhance the effect on macrophage cholesterol ester hydrolase activity and/or inhibit acyl CoA:cholesterol acyl transferase activity. Methods of using these compositions in the treatment and/or prevention of atherosclerosis as well as coronary heart disease and cardiovascular disease are also provided.

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Additional details

Identifiers

Patent application number
US 70170910 A
Patent number
US 8703698 B2
Other
oai:uchicago.tind.io:9427

Dates

Patent filed
2010-02-08

UChicago Information

Division(s)
Physical Sciences Division
Department(s)
Chemistry