Published August 16, 2011 | Version v1
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Methods of activating NKT cells

  • 1. University of Chicago
  • 2. Scripps Research Institute
  • 3. Brigham Young University

Description

Provided are methods of activating an NKT cell which include a step of contacting the NKT cell with a sufficient amount of isoglobotrihexosylceramide (iGb3) to induce secretion of a cytokine from the NKT cell, stimulate proliferation of the NKT cell or upregulate expression of a cell surface marker on the NKT cell. Methods of activating an NKT cell population in a subject are also provided.

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Additional details

Identifiers

Patent application number
US 21890605 A
Patent number
US 7998739 B2
Other
oai:uchicago.tind.io:8501

Dates

Patent filed
2005-09-02

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Pathology, Immunology, Medicine