Experiment Date2019-08-02 Experiment ID Notebook ID Project Experimenter Protocol Experiment Date2019-08-02 Experiment ID Notebook ID Project Experimenter Protocol 0. 3. 6. 9. 12. 15. 18. 21. 24. 27. 30. 33. 36. 39. 4979497.0000000 5517122.0000000 5961414.0000000 6446028.0000000 1.116765e+07 1.495391e+07 1.730939e+07 1.908412e+07 2.082979e+07 2.249152e+07 2.407791e+07 2.582694e+07 2.752725e+07 2.901489e+07 5761991.0000000 6427890.0000000 6935370.0000000 7481590.0000000 1.150701e+07 1.633034e+07 1.940488e+07 2.170472e+07 2.359278e+07 2.547328e+07 2.730287e+07 2.929007e+07 3.129439e+07 3.325633e+07 5787290.0000000 6563666.0000000 7117106.0000000 7740015.0000000 1.231521e+07 1.827915e+07 2.242316e+07 2.511839e+07 2.718314e+07 2.937979e+07 3.141367e+07 3.361726e+07 3.581087e+07 3.783112e+07 5573390.0000000 6390612.0000000 7039628.0000000 7701234.0000000 1.216614e+07 1.827705e+07 2.252786e+07 2.524982e+07 2.760315e+07 2.988476e+07 3.202088e+07 3.429132e+07 3.644374e+07 3.853689e+07 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7701234.0000000 7701234.0000000 1.908412e+07 2.352896e+07 2.170472e+07 2.293507e+07 2.511839e+07 2.281982e+07 2.524982e+07 2.524982e+07 1.865173e+07 2.292369e+07 2.457447e+07 2.178728e+07 2.589284e+07 2.301918e+07 2.731966e+07 2.731966e+07 2.273644e+07 2.324321e+07 2.728010e+07 2.186279e+07 2.779323e+07 2.318188e+07 2.756990e+07 2.756990e+07 2.758792e+07 2.356277e+07 2.763753e+07 2.274263e+07 2.919846e+07 2.285637e+07 2.826949e+07 2.826949e+07 2.871810e+07 2.217339e+07 2.860363e+07 2.178241e+07 2.929594e+07 2.455105e+07 2.970005e+07 2.970005e+07 WT Drp1 KO 259.92310000 314.70210000 295.61540000 306.75890000 342.10900000 305.21730000 343.89920000 337.71890000 254.034000000 306.606600000 334.701000000 291.407000000 352.657000000 307.883800000 372.090100000 365.403100000 309.667200000 310.880300000 371.551200000 292.417000000 378.540100000 310.060000000 375.498300000 368.750100000 375.743700000 315.154400000 376.419500000 304.184900000 397.679100000 305.706200000 385.026600000 378.107200000 391.136600000 296.571300000 389.577600000 291.341900000 399.006700000 328.372800000 404.510700000 397.241200000 WT DRP1 KO 259.92310000 314.70210000 295.61540000 306.75890000 342.10900000 305.21730000 343.89920000 337.71890000 254.03400000 306.60660000 334.70100000 291.40700000 352.65700000 307.88380000 372.09010000 365.40310000 309.667200000 310.880300000 371.551200000 292.417000000 378.540100000 310.060000000 375.498300000 368.750100000 375.743700000 315.154400000 376.419500000 304.184900000 397.679100000 305.706200000 385.026600000 378.107200000 391.136600000 296.571300000 389.577600000 291.341900000 399.006700000 328.372800000 404.510700000 397.241200000 WT DRP1 KO 0.83741700 0.99557990 0.95241010 0.97045100 1.10220300 0.96557410 1.10797000 1.06839500 0.818443800 0.969969200 1.078336000 0.921884400 1.136186000 0.974009700 1.198795000 0.997682200 0.983489300 1.197059000 0.925079600 1.219576000 0.980894300 1.209776000 1.210566000 0.997010700 1.212744000 0.962308000 1.281238000 0.967120700 1.240474000 1.260159000 0.938221800 1.255136000 0.921678400 1.285515000 1.038828000 1.303248000 0. 3. 6. 9. 12. 15. 18. 21. 24. 27. 30. 33. 36. 39. 6988909.0000000 7202362.0000000 7895698.0000000 8579239.0000000 1.407649e+07 1.807010e+07 2.160768e+07 2.488859e+07 2.790377e+07 3.087626e+07 3.360240e+07 3.635328e+07 3.911215e+07 4.156345e+07 6123973.0000000 6520758.0000000 7085271.0000000 7688188.0000000 1.093373e+07 1.442238e+07 1.761876e+07 2.069610e+07 2.354733e+07 2.640955e+07 2.900882e+07 3.145122e+07 3.401107e+07 3.652845e+07 7188732.0000000 7276987.0000000 7928842.0000000 8648088.0000000 1.227441e+07 1.624466e+07 1.985512e+07 2.319364e+07 2.627714e+07 2.920897e+07 3.224493e+07 3.480998e+07 3.750921e+07 4.008774e+07 6542760.0000000 6704992.0000000 7354515.0000000 7946194.0000000 1.131421e+07 1.482703e+07 1.827068e+07 2.153429e+07 2.451399e+07 2.743233e+07 3.029591e+07 3.280356e+07 3.564938e+07 3.803342e+07 6781392.0000000 7078365.0000000 7756704.0000000 8432114.0000000 1.308568e+07 1.704696e+07 2.055769e+07 2.384478e+07 2.677345e+07 2.964856e+07 3.248667e+07 3.513197e+07 3.781372e+07 4.035953e+07 6057404.0000000 6449105.0000000 7021564.0000000 7595732.0000000 1.105420e+07 1.465353e+07 1.800412e+07 2.114375e+07 2.403253e+07 2.691864e+07 2.956290e+07 3.211267e+07 3.482676e+07 3.712205e+07 7186068.0000000 7645772.0000000 8333638.0000000 9101524.0000000 1.267649e+07 1.691444e+07 2.079920e+07 2.438397e+07 2.762048e+07 3.069600e+07 3.378207e+07 3.644743e+07 3.932613e+07 4.200057e+07 7294093.0000000 7549696.0000000 8234374.0000000 8963870.0000000 1.263045e+07 1.690937e+07 2.065406e+07 2.406108e+07 2.728041e+07 3.016706e+07 3.305730e+07 3.591304e+07 3.882655e+07 4.156394e+07 7660809.0000000 8200464.0000000 9063204.0000000 9938139.0000000 1.485642e+07 1.959723e+07 2.374038e+07 2.742547e+07 3.083721e+07 3.415718e+07 3.735740e+07 4.006122e+07 4.300225e+07 4.593594e+07 7402158.0000000 7896820.0000000 8628879.0000000 9427924.0000000 1.347604e+07 1.796671e+07 2.201514e+07 2.566899e+07 2.905829e+07 3.228939e+07 3.551886e+07 3.835402e+07 4.130815e+07 4.422426e+07 7850330.0000000 7924312.0000000 8659003.0000000 9409894.0000000 1.326264e+07 1.762318e+07 2.162774e+07 2.520672e+07 2.866421e+07 3.187384e+07 3.494891e+07 3.789082e+07 4.080451e+07 4.353586e+07 7456704.0000000 7879584.0000000 8631388.0000000 9431578.0000000 1.329063e+07 1.771107e+07 2.162178e+07 2.519441e+07 2.835470e+07 3.126749e+07 3.393916e+07 3.687285e+07 3.967758e+07 4.226960e+07 1.124068e+07 1.156358e+07 1.209173e+07 1.268111e+07 1.954673e+07 2.695777e+07 3.092963e+07 3.346941e+07 3.547562e+07 3.747196e+07 3.941676e+07 4.124152e+07 4.318767e+07 4.541237e+07 1.094732e+07 1.137300e+07 1.181537e+07 1.233488e+07 1.798737e+07 2.464367e+07 2.864312e+07 3.133004e+07 3.341706e+07 3.540009e+07 3.746092e+07 3.929057e+07 4.123096e+07 4.348101e+07 1.067018e+07 1.097650e+07 1.147489e+07 1.190937e+07 1.686817e+07 2.328773e+07 2.741400e+07 2.985391e+07 3.191615e+07 3.368399e+07 3.560118e+07 3.700367e+07 3.871494e+07 4.066243e+07 1.050524e+07 1.067777e+07 1.115400e+07 1.154723e+07 1.667728e+07 2.304861e+07 2.701556e+07 2.927124e+07 3.158200e+07 3.324840e+07 3.516415e+07 3.649843e+07 3.690782e+07 3.999377e+07 7764826.0000000 8252748.0000000 9131080.0000000 1.000939e+07 1.489821e+07 1.964402e+07 2.382831e+07 2.730860e+07 3.050242e+07 3.389794e+07 3.724160e+07 3.995299e+07 4.299956e+07 4.586533e+07 7397725.0000000 8046512.0000000 8778069.0000000 9601277.0000000 1.437856e+07 1.902508e+07 2.312804e+07 2.674432e+07 3.011023e+07 3.309067e+07 3.635072e+07 3.926756e+07 4.209614e+07 4.504081e+07 7592158.0000000 8171946.0000000 8930402.0000000 9766259.0000000 1.372461e+07 1.839048e+07 2.271076e+07 2.642563e+07 2.981176e+07 3.308573e+07 3.626343e+07 3.919619e+07 4.213260e+07 4.521956e+07 7454518.0000000 7834570.0000000 8660455.0000000 9426291.0000000 1.355121e+07 1.812316e+07 2.212374e+07 2.569716e+07 2.898642e+07 3.194321e+07 3.483801e+07 3.768510e+07 4.068284e+07 4.348263e+07 0. 3. 6. 9. 12. 15. 18. 21. 24. 27. 30. 33. 36. 39. 7804692.0000000 8161100.0000000 8793500.0000000 9403708.0000000 6.250897e+07 6.398013e+07 6.590724e+07 6.763137e+07 6.930977e+07 7.091126e+07 7.265045e+07 7.416006e+07 7.596502e+07 7.772884e+07 9856054.0000000 1.021151e+07 1.077649e+07 1.139889e+07 1.485306e+07 1.774676e+07 1.987783e+07 2.171464e+07 2.331238e+07 2.483449e+07 2.635498e+07 2.777756e+07 2.948395e+07 3.097289e+07 1.058671e+07 1.095750e+07 1.148480e+07 1.216772e+07 1.562946e+07 1.890154e+07 2.120946e+07 2.304602e+07 2.479500e+07 2.628022e+07 2.804975e+07 2.944042e+07 3.113282e+07 3.279860e+07 1.092298e+07 1.136970e+07 1.199445e+07 1.260682e+07 1.674870e+07 2.038338e+07 2.297408e+07 2.502834e+07 2.690674e+07 2.860143e+07 3.029391e+07 3.176218e+07 3.362026e+07 3.528612e+07 7879624.00000000 8055844.00000000 8493784.00000000 8993994.00000000 2.985393e+07 3.152493e+07 3.293692e+07 3.415406e+07 3.538502e+07 3.658642e+07 3.786769e+07 3.930641e+07 4.077330e+07 4.221235e+07 9157139.00000000 9512335.00000000 9961134.00000000 1.050482e+07 1.388191e+07 1.694029e+07 1.900909e+07 2.075555e+07 2.227188e+07 2.367135e+07 2.511506e+07 2.637831e+07 2.803893e+07 2.952122e+07 9481683.00000000 9716595.00000000 1.008286e+07 1.056462e+07 1.356505e+07 1.628568e+07 1.831428e+07 1.995218e+07 2.126111e+07 2.256264e+07 2.400428e+07 2.528471e+07 2.663215e+07 2.798134e+07 8902784.00000000 9158381.00000000 9571003.00000000 1.000737e+07 1.353631e+07 1.597912e+07 1.801287e+07 1.950585e+07 2.071750e+07 2.209032e+07 2.291928e+07 2.480720e+07 2.621021e+07 2.734463e+07 7659943.00000000 7825451.00000000 8329120.00000000 8791950.00000000 2.045659e+07 2.262437e+07 2.421249e+07 2.538345e+07 2.671531e+07 2.785010e+07 2.920134e+07 3.049973e+07 3.185858e+07 3.328361e+07 8366284.00000000 8779204.00000000 9203089.00000000 9604811.00000000 1.317385e+07 1.602086e+07 1.803090e+07 1.969734e+07 2.096368e+07 2.223661e+07 2.349522e+07 2.479219e+07 2.631240e+07 2.764791e+07 8679286.00000000 9101048.00000000 9508900.00000000 9934984.00000000 1.331209e+07 1.601217e+07 1.805572e+07 1.969838e+07 2.109634e+07 2.237721e+07 2.353439e+07 2.483913e+07 2.622863e+07 2.759853e+07 9098611.00000000 9058375.00000000 9386185.00000000 1.005654e+07 1.358924e+07 1.658377e+07 1.868436e+07 2.028844e+07 2.180990e+07 2.302461e+07 2.433301e+07 2.559210e+07 2.696909e+07 2.834743e+07 6408296.0000000 6482006.0000000 7152628.0000000 7851718.0000000 1.535877e+07 1.872010e+07 2.199623e+07 2.491840e+07 2.770442e+07 3.049990e+07 3.300042e+07 3.540795e+07 3.793454e+07 4.026464e+07 5771819.0000000 6095462.0000000 6607861.0000000 7229384.0000000 1.048532e+07 1.370394e+07 1.666098e+07 1.960353e+07 2.229877e+07 2.484898e+07 2.741185e+07 2.980615e+07 3.226413e+07 3.471032e+07 6225392.0000000 6482616.0000000 7022792.0000000 7564930.0000000 1.056470e+07 1.372671e+07 1.667844e+07 1.955399e+07 2.223406e+07 2.475766e+07 2.733864e+07 2.973185e+07 3.215745e+07 3.464077e+07 6495970.0000000 6705402.0000000 7321050.0000000 7879420.0000000 1.111582e+07 1.437308e+07 1.753375e+07 2.046216e+07 2.328105e+07 2.600787e+07 2.874029e+07 3.121096e+07 3.375964e+07 3.638339e+07 9271760.0000000 9333994.0000000 9908941.0000000 1.033943e+07 1.744614e+07 2.083150e+07 2.304189e+07 2.463962e+07 2.613862e+07 2.771236e+07 2.916446e+07 3.064598e+07 3.220923e+07 3.379674e+07 8167474.0000000 8358061.0000000 8793770.0000000 9178326.0000000 1.248439e+07 1.510346e+07 1.692206e+07 1.837662e+07 1.958978e+07 2.078006e+07 2.204402e+07 2.302954e+07 2.428516e+07 2.585869e+07 8862307.0000000 8835832.0000000 9235461.0000000 9638425.0000000 1.302200e+07 1.627452e+07 1.867379e+07 2.055090e+07 2.220403e+07 2.375137e+07 2.517182e+07 2.669501e+07 2.826692e+07 2.984849e+07 8744013.0000000 8794544.0000000 9205563.0000000 9615388.0000000 1.316229e+07 1.596298e+07 1.800738e+07 1.962544e+07 2.090593e+07 2.220328e+07 2.354720e+07 2.472681e+07 2.605271e+07 2.729229e+07 Buffer Succinate 4.631094e+07 4.787592e+07 4.563356e+07 4.851999e+07 4.578331e+07 5.123010e+07 4.516725e+07 5.149340e+07 4.687668e+07 4.907204e+07 4.551587e+07 5.027865e+07 4.445710e+07 4.687435e+07 4.621473e+07 4.671589e+07 4.633430e+07 5.034065e+07 4.596823e+07 5.090660e+07 4.608150e+07 5.044150e+07 4.658578e+07 4.961388e+07 Buffer Succinate 1.009365 1.043474 0.9946011 1.057512 0.997865 1.116580 0.9844377 1.122319 1.021695 1.069544 0.992036 1.095843 0.9689597 1.021645 1.007268 1.018191 1.009874 1.097194 1.001895 1.109529 1.004364 1.099392 1.015355 1.081354 WT DRP1 KO 0.8779403 0.9823578 1.0189820 0.9524380 1.0541800 1.0895070 1.0488980 1.0488980 2.5992310 3.2046130 2.9561540 3.1237260 3.4210910 3.1080290 3.4389910 3.4389910 2.5403400 3.1221760 3.3470100 2.9673980 3.5265700 3.1351810 3.7209010 3.7209010 3.0966720 3.1656940 3.7155130 2.9776820 3.7854000 3.1573410 3.7549830 3.7549830 3.7574380 3.2092180 3.7641940 3.0975160 3.9767910 3.1130070 3.8502670 3.8502670 3.9113670 3.0199860 3.8957760 2.9667350 3.9900680 3.3438200 4.0451070 4.0451070 Baseline Succinate Succinate+3nM Ca2+ Succinate+30nM Ca2+ Succinate+300nM Ca2+ Succinate+3mM Ca2+ 0.8779403 2.5992310 2.5403400 3.0966720 3.7574380 3.9113670 1.0189820 2.9561540 3.3470100 3.7155130 3.7641940 3.8957760 1.0541800 3.4210910 3.5265700 3.7854000 3.9767910 3.9900680 1.0488980 3.4389910 3.7209010 3.7549830 3.8502670 4.0451070 0.9823578 3.2046130 3.1221760 3.1656940 3.2092180 3.0199860 0.9524380 3.1237260 2.9673980 2.9776820 3.0975160 2.9667350 1.0895070 3.1080290 3.1351810 3.1573410 3.1130070 3.3438200 1.0488980 3.4389910 3.7209010 3.7549830 3.8502670 4.0451070