Published December 13, 2012 | Version v1
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Modulation of Cell Barrier Dysfunction

Description

The invention provides prophylactic and therapeutic methods for administering a μ-opioid receptor antagonist, e.g., N-methylnaltrexone or a salt thereof, to treat cell barrier diseases and disorders, such as endothelial and epithelial cell barrier diseases and disorders, e.g., inflammatory bowel disease. Methods of reducing the symptoms of inflammatory bowel disease and the risk of developing inflammatory bowel disease are also provided.

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Additional details

Identifiers

Patent number
US 201213483932 A
Patent application number
US 2012/0316190 A1
Other
oai:uchicago.tind.io:8458

Dates

Patent filed
2012-05-30

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Surgery, Anesthesia and Critical Care