Published July 18, 2013 | Version v1
Patent Open

Methods and/or Use of Oligonucleotide Conjugates Having Varied Degrees of Labeling for Assays and Detections

Description

The present disclosure is directed to methods and/or uses of oligonucleotide conjugates having varied degrees of labeling for assays and detections and related systems and/or kits. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein.

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Additional details

Identifiers

Patent number
US 201113302819 A
Patent application number
US 2013/0184184 A1
Other
oai:uchicago.tind.io:8493

Dates

Patent filed
2011-11-22

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Molecular Genetics and Cell Biology