Published October 25, 2018 | Version v1
Patent Open

HEAT-INDUCIBLE SELF-ASSEMBLING PROTEIN DOMAINS

Description

A heat-inducible self-assembling fusion protein that includes a self-assembly domain and a target protein, wherein the self-assembly domain remains folded during assembly. The aggregate forming fusion protein can be induced to form protein aggregates conjugated to a target protein. The aggregates can be used similarly to beads in many laboratory protocols and other applications. Also disclosed are methods of making and using the protein aggregates.

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Additional details

Identifiers

Patent application number
US 201515521330 A
Patent number
US 2018/0305699 A1
Other
oai:uchicago.tind.io:8080

Dates

Patent filed
2015-10-23

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Biochemistry and Molecular Biology, Human Genetics