Published September 18, 2014 | Version v1
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YEAST SCREENS FOR TREATMENT OF HUMAN DISEASE

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Patent applicant:

Description

Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are provided using a yeast system. The methods of the invention provide a rapid and cost-effective method to screen for compounds that prevent protein misfolding and/or protein fibril formation and/or protein aggregation which includes numerous neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, Huntington's disease as well as non-neuronal diseases such as type 2 diabetes.

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Additional details

Identifiers

Patent number
US 201314105500 A
Patent application number
US 2014/0273074 A1
Other
oai:uchicago.tind.io:9036

Dates

Patent filed
2013-12-13

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Molecular Genetics and Cell Biology