Published April 5, 2011 | Version v1
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Constitutive gene expression in conjunction with ionizing radiation

Description

The present disclosure demonstrates the successful use of constitutive promoters operatively linked to genes encoding radiosensitizing or radioprotecting factors, administered to cells, tissues, or patients in conjunction with radiation exposure. Also disclosed are pharmacological preparations to be used to increase the levels of radiosensitizing compounds such as TNF-α, or radioprotective compounds such as MnSOD, in specified tissues or tumors of a subject.

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Additional details

Identifiers

Patent number
US 1942808 A
Patent application number
US 7919310 B2
Other
oai:uchicago.tind.io:9538

Dates

Patent filed
2008-01-24

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Microbiology, Radiation and Cellular Oncology, Pathology