Published October 29, 2015 | Version v1
Patent Open

METHODS AND COMPOSITIONS INVOLVING RAD51 INHIBITORS

Description

The present invention concerns methods and compositions involving inhibitors and of RAD51, a protein involved in homologous recombination. In some embodiments, there are methods for sensitizing cells to the effects of DNA damaging agents, which can have particular applications for cancer patients. In some embodiments of the invention, the RAD51 inhibitor is a small molecule that directly affects RAD51 activity, such as its ability to promote filament formation.

Files

US10912761.pdf

Files (2.1 MB)

Name Size Download all
md5:8cb3cf033a686c54f86ccad81d0af94f
2.1 MB Preview Download

Additional details

Identifiers

Patent number
US 201314648115 A
Patent application number
US 2015/0306069 A1
Other
oai:uchicago.tind.io:7351

Dates

Patent filed
2013-11-27

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Radiation and Cellular Oncology