Published July 7, 2009 | Version v1
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Gastrokines and derived peptides including inhibitors

Description

A novel group of gastrokines called Gastric Antrum Mucosal Protein is characterized. A member of the group is designated AMP-18. AMP-18 genomic DNA, cDNA and the AMP-18 protein are sequenced for human, mouse and pig. The AMP-18 protein and active peptides derived from it are cellular growth factors. Surprisingly, peptides capable of inhibiting the effects of the complete protein, are also derived from the AMP-18 protein. Control of mammalian gastro-intestinal tissues growth and repair is facilitated by the use of the proteins, making the proteins candidates for therapies.

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Additional details

Identifiers

Patent application number
US 47352404 A
Patent number
US 7557083 B2
Other
oai:uchicago.tind.io:9050

Dates

Patent filed
2004-10-21

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Molecular Genetics and Cell Biology, Medicine